CL201

ORAGANIC CHEMISTRY

FACULTY MEMBER:- Prof. N.SULOCHANA.

OBJECTIVE :This paper serves the students to learn synthetic routes to many types of important organic compounds and their characterizations.

1. REACTIONS AND REAGENTS:

Organometallic compounds - Grignard reagent - synthesis of different types of compounds like alcohol, aldehyde, acid, amine and organometallic. Acetoacetic ester - tautomerism - base hydrolysis - acid hydrolysis - malonic ester - cyano acetic ester - synthesis of dicarboylic acids and unsaturated acids.

2. CARBOHYDRATES:

R, S, configuration, mutarotation, conversions - glucose to fructose and vice versa, sucrose - structural elucidation, extraction, reactions, starch and cellulose - structural details, applications

3. ALICYCYCLIC COMPOUNDS, AROMATIC COMPOUNDS, FATS AND OILS:

Alicyclic compounds - nomenclature - synthesis of alicyclic compounds using carbon - acroyloin condensation - Diels Alder reaction, Freunds’s synthesis - bayer's strain theory postulates, drawbacks - theory of strainless rings - conformations of cyclohexane. Coal tar distillation, separation of benzene, toluene, phenol and naphthalene - Aromaticity exhibited by these compounds. Fats and oils - Saponification- hydrogenation of oils

4. AMINO ACIDS, PROTEINS AND DYES:

Amino acids and proteins- classification - synthesis of amino acids - reactions of carboxyl group and amino group - peptide linkage - end group analysis - colour reaction of proteins- denaturation. Dyes - colors and constitution - chromophores and auxochromes- Quinine theory and electron theory of dyes- preparation-colour and application of azodyes - acidic. basic, mordant, direct azodyes - Triphenylmethane dyes - malachite green, crystal violet, Rosaniline, prosaniline mordant dyes- application, vat dyes-indigo-synthesis and application

5 HETEROCYCLIC COMPOUNDS AND NATURAL PRODUCTS:

Heterocyclic compounds-synthesis and reaction of pyrrole ,furan ,thiophene, pyridine, quinine, isoquinoline. Alkaloids-Isolation from natural products-colour reaction-structural elucidation of nicotine. Terpenoids- Isolation - Isoprene rule-structural elucidation of citral.

TEXTBOOKS:

1. I.L. Finar, "Organic Chemistry", (Vol. I & II) 5th Edn., ELBS, London 1975.
2. Morrison and Boyd, " A Text Book of Organic Chemistry", 5th and 6th Edn., Prentice Hall of India, 1996.